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1.
Arq Asma Alerg Imunol ; 7(3): 298-301, Jul.Set.2023. ilus
Article in English, Portuguese | LILACS | ID: biblio-1524182

ABSTRACT

A dermatite de contato pigmentada se destaca por sua raridade, sendo associada a inúmeros alérgenos cosméticos e têxteis. Acomete predominantemente mulheres de meia idade e fototipos altos. O teste de contato é imprescindível para a identificação do agente causal. O tratamento indicado consiste no afastamento do agente causal, no uso de fotoprotetores, clareadores tópicos e, por vezes, procedimentos dermatológicos abrasivos. Relatamos um caso de dermatite de contato pigmentada por cosmético motivado pela exuberância clínica e desfecho satisfatório, ressaltando a importância da suspeição diagnóstica e do manejo adequado impactando neste desfecho.


Pigmented contact dermatitis is a rare condition associated with numerous cosmetic and textile allergens. It predominantly affects middle-aged women with high phototypes. The patch test is essential to identify the causative agent. Treatment includes removal of the causative agent, sunscreen use, administration of topical bleaching agents, and occasionally abrasive dermatologic procedures. We report a case of pigmented cosmetic contact dermatitis motivated by its clinical exuberance and satisfactory outcome, emphasizing the importance of diagnostic suspicion and adequate management impacting this outcome.


Subject(s)
Humans , Female , Middle Aged
2.
Arq. Asma, Alerg. Imunol ; 5(2): 199-202, abr.jun.2021. ilus
Article in Portuguese | LILACS | ID: biblio-1398932

ABSTRACT

A prática de tatuagens é muito antiga e atualmente tornou-se extremamente popular, porém traz consigo riscos que não podem ser ignorados. As tintas utilizadas nas tatuagens são um fator importante para o aparecimento de reações adversas. A reação de hipersensibilidade aos pigmentos das tintas é uma das mais comuns. Entre elas, encontram-se reações alérgicas tipo dermatites de contato ou reações de fotossensibilidade, sendo esta última o motivo deste relato. O tratamento indicado é o uso de corticoides e a fotoproteção. Neste artigo, discorreremos especificamente sobre a reação de fotossensibilidade ao pigmento azul, com o relato de um caso e breve revisão da literatura.


Tattooing is a very old practice that has become extremely popular in recent years; however, it carries risks that cannot be ignored. The inks used in tattoos are an important factor for the appearance of adverse reactions. Hypersensitivity reactions to the pigments in the inks are some of the most common. These include allergic reactions such as contact dermatitis or photosensitivity reactions, the latter being the reason for this report. The recommended treatment is the use of corticosteroids and photoprotection. In this article, we will specifically discuss the photosensitivity reaction to the blue pigment with a case report and a brief literature review.


Subject(s)
Humans , Male , Adult , Tattooing , Dermatitis, Photoallergic , Hypersensitivity , Therapeutics , Adrenal Cortex Hormones , Coloring Agents , Histamine Antagonists , Ink
3.
An. bras. dermatol ; 95(6): 751-753, Nov.-Dec. 2020. graf
Article in English | LILACS, ColecionaSUS | ID: biblio-1142116

ABSTRACT

Abstract Paget's disease is a rare disorder of the nipple and/or the areola that is characterized by an erythematosquamous lesion and is often associated with in situ or invasive breast carcinoma. The authors present an atypical, exuberant case that had evolved over eight years, emphasizing the importance of early diagnosis.


Subject(s)
Humans , Breast Neoplasms/diagnosis , Paget's Disease, Mammary , Thorax/diagnostic imaging , Ulcer , Nipples
6.
An. bras. dermatol ; 94(1): 37-41, Jan.-Feb. 2019. graf
Article in English | LILACS | ID: biblio-983742

ABSTRACT

Abstract: Background: Leprosy is a chronic, infectious disease that affects the skin and the peripheral nervous system and can lead to permanent disability and/or deformity. Objectives: To identify the distribution and to quantify the spatial dependence of the detection rates of new cases of Hansen's disease in the State of São Paulo, correlating with socioeconomic variables. Methods: Ecological and exploratory study with data on the detection rates of new cases of Hansen's disease among residents of São Paulo State municipalities between 2009-2012. The average rate per 10,0000 inhabitants was estimated. Information on the proportion of the population with low-income and the values of the Gini index were obtained. Thematic maps were constructed with the average rates and with those obtained by the Bayesian estimator; Moran and Kernel maps were also constructed. Spatial analysis by TerraView program. An alpha of 5% was adopted. Results: In total, 7163 new cases of Hansen's disease were recorded throughout the state. The average rate per 10,000 inhabitants, was 0.71 (SD = 1.06), ranging from zero to 12.87, with higher rates in the west of the State, in the metropolitan area of the capital and the Paraiba Valley. Municipalities with high priority for intervention were located in the west and northwest of the State. There was no correlation between rates with Gini index and low income. Study limitations: Possible inconsistency of Hansen's disease notification database regarding information quantity, quality and processing. Conclusions: This study identified the distribution and quantified the spatial dependence of the detection rates of new cases of Hansen's disease in the State of São Paulo, corroborating previous studies and serving as a subsidy to health managers.


Subject(s)
Humans , Male , Female , Spatial Analysis , Leprosy/epidemiology , Socioeconomic Factors , Brazil/epidemiology , Bayes Theorem , Cities/epidemiology , Geographic Information Systems
7.
Surg. cosmet. dermatol. (Impr.) ; 11(1): 31-34, Jan.-Mar. 2019. ilus, tab
Article in English, Portuguese | LILACS | ID: biblio-1008241

ABSTRACT

Introdução: A cicatrização é um fenômeno que ocorre após lesão tecidual e envolve mecanismos celulares e moleculares complexos. Os fatores de crescimento parecem ser um complemento eficaz e seguro no tratamento das feridas. Objetivo: Avaliar a cicatrização de feridas após eletrocoagulação, comparando-se o veículo isolado à sua associação com o fator de crescimento epidérmico. Métodos: Ensaio clínico duplo-cego em Serviço de Dermatologia entre 2016 e 2018. Incluídos pacientes de ambos os sexos, acima de 18 anos, submetidos à eletrocoagulação de duas lesões e posterior aplicação de veículo (cold cream) em uma e fator de crescimento epidermico em cold cream na outra. Avaliações com sete, 14 e 28 dias, analisaram: eritema, edema, crosta, secreção e cicatrização. Utilizou-se o teste binomial para duas proporções e o teste exato de Fisher para dados dicotômicos. Resultados: Em relação a eritema, edema, crosta e secreção foram encontrados resultados variáveis, ora favorecendo o veículo, ora o fator de crescimento, porém sem significância estatística. Quanto à cicatrização, a epitelização mostrou-se mais rápida com fator de crescimento epidermico (p<0,05). Conclusões: Os resultados deste estudo, que avaliou o impacto do fator de crescimento epidérmico no processo de cicatrização, corroboram os dados da escassa literatura atual e servem de base para estudos futuros.


Introduction: Healing is a phenomenon that occurs after tissue injury and involves complex cellular and molecular mechanisms. Growth factors seem to be an effective and safe complement for the treatment of wounds. Objective: To evaluate wound healing after electrocoagulation, comparing the vehicle in isolation and its association with epidermal growth factor. Methods: Double-blind clinical trial in a Dermatology service between 2016 and 2018. Patients of both genders, older than 18 years of age, submitted to electrocoagulation of two lesions and subsequent application of the vehicle (cold cream) on one and epidermal growth factor in cold cream on the other were included. Evaluations after 7, 14 and 28 days, analysed erythema, edema, crusting, discharge and healing. Analyzed: edema, edema, crusting, discharge and healing. The binomial test was used for two ratios and Fisher's exact test was used for dichotomic data. Results: Variable results were found regarding erythema, edema, crusting and discharge, sometimes favoring the vehicle, sometimes the growth factor, however with no statistical significance. Regarding healing, epithelialization was quicker with epidermal growth factor (p<0.05). Conclusions: This study evaluated the impact of epidermal growth factor in the healing process, and its results reinforce scarce data of the current literature and are a foundation for future studies.


Subject(s)
Wound Healing , Dermatology , Epidermal Growth Factor
8.
An. bras. dermatol ; 93(5): 730-732, Sept.-Oct. 2018. graf
Article in English | LILACS | ID: biblio-949940

ABSTRACT

Abstract: Neutrophilic dermatosis of the dorsal hands is considered a rare and localized variant of Sweet's syndrome. Although the etiology is unknown, there are reports of association with infections, neoplasias, autoimmune diseases and medications. Histopathology shows a dense neutrophilic inflammatory infiltrate in the dermis. Treatment is based on the administration of systemic corticosteroids; however, a combination of medications is useful, given the frequency of relapses. The authors report a classic and clinically exuberant case of neutrophilic dermatosis of the dorsal hands, with excellent response to oral dapsone treatment, and offer a brief literature review.


Subject(s)
Humans , Female , Middle Aged , Sweet Syndrome/drug therapy , Dapsone/therapeutic use , Hand Dermatoses/drug therapy , Anti-Infective Agents/therapeutic use , Sweet Syndrome/complications , Hand Dermatoses/etiology
9.
Surg. cosmet. dermatol. (Impr.) ; 10(2): 172-175, Abr.-Jun. 2018. ilus.
Article in English, Portuguese | LILACS | ID: biblio-913551

ABSTRACT

Descrito por Jadassohn e também conhecido como nevo organoide, o nevo sebáceo é considerado hamartoma que exibe má-formação folicular, sebácea, écrina e apócrina de graus variados. Durante a idade adulta, de dez a 30% dos pacientes com nevo sebáceo de Jadassohn têm risco de desenvolver neoplasia cutânea ou anexial. Relatamos caso de paciente com nevo sebáceo de Jadassohn associado a múltiplas neoplasias (benignas e malignas) de diferentes linhagens e ressaltamos a importância do conhecimento dessa entidade e do exame do couro cabeludo por parte do dermatologista.


Described by Jadassohn and also known as organoid nevus, nevus sebaceous is considered a hamartoma that exhibits follicular, sebaceous, eccrine and apocrine malformations of varying degrees. Between 10% and 30% of patients with sebaceous nevi of Jadassohn are at risk of developing cutaneous or adnexal neoplasia during adulthood. The authors describe the case of a patient with nevus sebaceous of Jadassohn associated with multiple tumors (benign and malignant) of different strains, highlighting the importance of the dermatologist physician's knowing this entity and how to perform an examination of the scalp.


Subject(s)
Neoplasms , Carcinoma, Basal Cell
10.
An. bras. dermatol ; 93(2): 294-296, Mar.-Apr. 2018. tab, graf
Article in English | LILACS | ID: biblio-1038268

ABSTRACT

Abstract: The vulva corresponds to the external female genitalia. Special features of this region favor a wide range of diseases, whose knowledge allows for better clinical management, impacting on the quality of life. This is a cross-sectional and descriptive study carried out at a vulvar pathology outpatient clinic, between May and December/ 2015. Data obtained from a standard form included demographic parameters, habits, and vulvar dermatosis and allowed to identify the epidemiological profile of patients with vulvar dermatosis treated in this outpatient clinic and to determine the most prevalent dermatoses. Our results, partially concordant with the literature, provide original data that should stimulate further studies


Subject(s)
Humans , Female , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Skin Diseases/epidemiology , Vulvar Diseases/epidemiology , Ambulatory Care Facilities/statistics & numerical data , Socioeconomic Factors , Brazil/epidemiology , Prevalence , Cross-Sectional Studies , Age Distribution
11.
Rev. Soc. Bras. Clín. Méd ; 15(4): 246-251, 20170000. tab, graf, ilus
Article in Portuguese | LILACS | ID: biblio-877082

ABSTRACT

OBJETIVO: Identificar o perfil epidemiológico de pacientes com psoríase e avaliar o impacto da doença na qualidade de vida deles. MÉTODOS: Estudo transversal e descritivo, realizado em um ambulatório de referência, entre 2013 e 2014. Foram incluídos indivíduos de ambos os sexos com mais de 18 anos. Variáveis clínicas e epidemiológicas foram estudadas. Para análise do impacto na qualidade de vida, foi utilizado o Dermatology Life Quality Index. A severidade da psoríase foi determinada pelo uso ou não de terapia sistêmica. RESULTADOS: Foram incluídos 41 indivíduos, sendo a maioria formada por homens (52,2%), com idade média da amostra 54,2 anos (desvio padrão 13,0), brancos (76,0%), com predomínio de analfabetos e com Ensino Fundamental incompleto (37,0% cada). O uso de terapia sistêmica foi referido por 73,0% da amostra, sendo o metotrexato a medicação mais utilizada (63,1%). A forma clínica mais prevalente foi a generalizada (62,0%), com predomínio de casos de severidade moderada a grave (73,1%). O Dermatology Life Quality Index médio da amostra foi de 5,6 (desvio padrão de 5,1). CONCLUSÃO: Ressaltam-se a necessidade e a importância da avaliação global do paciente psoriático, permitindo individualizar tratamentos, melhorar a relação médico-paciente e obter melhores resultados que satisfaçam a ambos: profissional e paciente.(AU)


Objective: To identify the epidemiological profile of, and to evaluate the impact on quality of life of patients with psoriasis. METHODS: Cross-sectional and descriptive study conducted at a reference outpatient clinic from 2013 to 2014. Individuals of both genders and over 18 years of age were included. Clinical and epidemiological variables were studied. The Dermatology Life Quality Index was used to analyze the impact on quality of life. The severity of psoriasis was determined by the use or not of systemic therapy. RESULTS: Forty-one individuals were included, with most of them being males (52.2%); mean age was 54.2 years (SD=13.0), white (76.0%), predominance of illiteracy and incomplete primary education (37.0% each); the use of systemic therapy was reported by 73.0%. Methotrexate was the most used medication (63.1%). The generalized form was the most prevalent (62.0%), with a predominance of moderate to severe severity (73.1%). The mean Dermatology Life Quality Index of the sample was 5.6 (SD=5.1). CONCLUSION: The need for the global evaluation of the psoriatic patient, along with its importance, are highlighted, allowing individualization of treatments, improvement of doctor-patient relationship, and achievement of better results that satisfy both the professional and the patient.(AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Psoriasis/epidemiology , Quality of Life , Surveys and Questionnaires , Hospitals, University
13.
An. bras. dermatol ; 91(4): 437-441, July-Aug. 2016. tab, graf
Article in English | LILACS | ID: lil-792444

ABSTRACT

Abstract: Background: Cutaneous melanoma is a skin cancer with low incidence but high mortality rates. The South region of Brazil has the highest death rates by melanoma per 100,000 inhabitants of the country. Little is known about the spatial distribution of this malignancy in southern Brazil. Objectives: Identify the spatial patterns of deaths from cutaneous melanoma in South region of Brazil, using geoprocessing tools. Methods: This is an ecological and exploratory study of death information by cutaneous melanoma obtained from portal Datasus, for Brazil's southern region, from January 2008 to December 2012. Deaths were separated by gender and rates per 100,000 inhabitants were calculated and used to compile thematic maps, Moran maps and Kernel maps, using TerraView software. It was adopted an alpha = 5%. Results: There were data on 2378 deaths from cutaneous melanoma in the study period. High rates were identified in the northern and littoral regions of Rio Grande do Sul; the northeast of Santa Catarina; and west of Paraná - for the total population, with minor differences detected and indicated regarding gender. The global Moran index presented p-values of 0.03, 0.04 and 0.03, respectively, for male, female and overall deaths. All the micro-regions that showed high priority for intervention were detected in the Rio Grande do Sul. Conclusion: Spatial clusters of micro-regions with high death rates from cutaneous melanoma in South region of Brazil were identified, serving as an important tool for health managers.


Subject(s)
Humans , Male , Female , Skin Neoplasms/mortality , Melanoma/mortality , Reference Values , Brazil/epidemiology , Cluster Analysis , Sex Factors , Incidence , Sex Distribution , Geographic Information Systems , Spatial Analysis
14.
Rev. Soc. Bras. Clín. Méd ; 14(2): 95-100, 2016.
Article in Portuguese | LILACS | ID: biblio-1250

ABSTRACT

OBJETIVOS: Avaliar a coexistência da psoríase e comorbidades relacionadas à síndrome metabólica, e identificar a associação de características dessa dermatose (gravidade, forma clínica e tipo de tratamento) com essas comorbidades. MÉTODOS: Trata-se de um estudo transversal e descritivo de base hospitalar, envolvendo indivíduos com psoríase em acompanhamento em um ambulatório de referência, de 2014 a 2015, sem restrições para seleção dos mesmos. A análise dos dados, obtidos por meio de questionário, avaliação clínica e exames complementares, foi inicialmente descritiva e, posteriormente, por regressão logística univariada. RESULTADOS: Foram incluídos 59 indivíduos. Destes, 55,9% apresentaram obesidade abdominal, 72,9% hipertensão arterial e 62,7% redução da HDL-c. A presença de psoríase de maior gravidade (Índice de Gravidade da Psoríase por Área − PASI>10) indicou maior chance para a ocorrência de hipertensão arterial, elevação da glicemia e de triglicerídeos; pacientes com forma clínica não vulgar apresentaram maior chance para todas as comorbidades, exceto para elevação de triglicerídeos, e pacientes em uso de medicação sistêmica apresentaram maior chance para ocorrência de obesidade abdominal, elevação da glicemia e de triglicerídeos. CONCLUSÕES: Psoríase e comorbidades relacionadas à síndrome metabólica coexistiram. Possivelmente, as formas clínicas não vulgar, a psoríase grave e o tratamento sistêmico com essas comorbidades estão associadas


OBJECTIVE: To evaluate the coexistence of psoriasis with metabolic syndrome-related comorbidities, and to identify the association of this dermatosis features (severity, clinical presentation and type of treatment) with these comorbidities. METHODS: This is a hospital based, cross-sectional and descriptive study involving individuals with psoriasis attended in a reference outpatient clinic, from 2014 to 2015, with no selection restrictions. Data were obtained through a questionnaire, clinical evaluation and laboratory tests; data analysis was first descriptive and, subsequently, by univariate logistic regression. RESULTS: Fifty-nine subjects were included. Among these, 55.9% had abdominal obesity, 72.9% had arterial hypertension, and 62.7% had decrease in HDL cholesterol. The presence of more severe psoriasis (Psoriasis Area Severity Index - PASI>10) indicated increased odds for the occurrence of arterial hypertension, high blood glucose and triglycerides levels; patients with clinical presentations other than psoriasis vulgaris had increased odds to all comorbidities, except for high triglycerides levels, and patients using systemic medications had increased odds to abdominal obesity, high blood glucose and triglycerides levels. CONCLUSIONS: There was coexistence of psoriasis with metabolic syndrome-related comorbidities. There is possible association of clinical presentations other than psoriasis vulgaris, severe psoriasis and systemic treatment with these comorbidities.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Psoriasis/epidemiology , Comorbidity , Hospitals, University , Metabolic Syndrome/epidemiology , Prevalence , Psoriasis/ethnology
15.
Surg. cosmet. dermatol. (Impr.) ; 8(2): 173-177, Abr.-Jun. 2016. ilus
Article in English, Portuguese | LILACS | ID: biblio-874911

ABSTRACT

O vitiligo é despigmentação adquirida caracterizada pela perda parcial ou total dos melanócitos da epiderme. Inúmeras modalidades terapêuticas foram propostas para seu tratamento. Nos casos de vitiligo estável os tratamentos cirúrgicos são a preferência. O enxerto por raspagem epidérmica é uma variante da técnica de microenxertos por punch. Constitui técnica nova, simples e de baixo custo, com altas taxas de repigmentação. O objetivo deste relato é demonstrar a experiência dos autores com essa técnica e discutir os resultados obtidos numa série inicial de dois casos (três lesões).


Vitiligo is an acquired depigmentation characterized by partial or total loss of epidermal melanocytes. Many therapeutic modalities have been proposed for its treatment. In cases of stable vitiligo surgical treatments are preferred. Grafting by epidermal scraping is a variant of micrografts by punch technique. It is a new, simple and low cost technique, with high rates of repigmentation. The objective of this report is to demonstrate the authors' experience with this technique and discuss the results in an initial series of two cases (three lesions).

16.
An. bras. dermatol ; 89(5): 745-750, Sep-Oct/2014. tab
Article in English | LILACS | ID: lil-720804

ABSTRACT

BACKGROUND: Nonmelanoma skin cancer is the most common form of cancer in humans and also the malignant disease that is increasingly common among kidney transplant recipients. OBJECTIVE: To determine the epidemiological characteristics of renal transplant recipients with nonmelanoma skin cancer seen at a referral transplantation center. METHODS: Cross-sectional descriptive study with renal transplant recipients presenting nonmelanoma skin cancer, treated at a transplantation referral center between 08/01/2004 and 08/31/2009. Analyzed variables were: gender, age, skin phototype, occupational and recreational sun exposure, use of photoprotection, personal and family history of non-melanoma skin cancer, clinical type and location, time between transplantation and the appearance of the first nonmelanoma skin cancer, occurrence of viral warts, timing of transplantation, type of donor, cause of kidney failure, previous transplants, comorbidities, pre-transplant dialysis, type and duration of dialysis. RESULTS: 64 subjects were included. Males - 71.9%; low skin phototypes (up to Fitzpatrick III) - 89%; mean age - 57.0 years - and mean age at transplant - 47.3 years; sun exposure - 67.2% occupational - and 64.1% recreational; photoprotection - 78.2% (although only 34.4% in a regular manner); squamous cell carcinoma - 67.2%; squamous cell carcinoma/basal cell carcinoma ratio - 2:1; personal history of nonmelanoma skin cancer - 25% - and family history - 10.9%; location at photoexposed area - 98.4%; average latency time between transplantation and first nonmelanoma skin cancer appearance - 78.3 months; viral warts (HPV) after transplant - 53.1%; average timing of transplantation - 115.5 months; living donor - 64.1%; triple regimen (antirejection) - 73.2%; comorbidities - 92.2%; pre-transplant dialysis - 98.4%; hemodialysis - 71.7%; average duration of dialysis - 39.1 months; previous transplants - 3.1%; hypertension as cause of renal failure ...


Subject(s)
Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Carcinoma, Basal Cell/etiology , Carcinoma, Squamous Cell/etiology , Kidney Transplantation/adverse effects , Skin Neoplasms/etiology , Brazil , Cross-Sectional Studies , Carcinoma, Basal Cell/epidemiology , Carcinoma, Squamous Cell/epidemiology , Immunocompromised Host , Immunosuppression Therapy/adverse effects , Immunosuppressive Agents/adverse effects , Risk Assessment , Risk Factors , Skin Neoplasms/epidemiology , Time Factors
17.
An. bras. dermatol ; 88(6,supl.1): 179-182, Nov-Dec/2013. graf
Article in English | LILACS | ID: lil-696801

ABSTRACT

Porokeratosis is a disorder of epidermal keratinization characterized by annular plaques with an atrophic center and hyperkeratotic edges, and includes a heterogeneous group of disorders that are mostly inherited in an autosomal dominant form. This report describes a 5 year-old female patient, with porokeratosis of Mibelli confirmed histopathologically. The rarity of this disorder, its clinical exuberance and the destructive character of the lesions, as well as the facial and mucosal involvements, unusual in this form of porokeratosis, and also its onset in early childhood motivated this report.


A poroqueratose é uma desordem da queratinização epidérmica caracterizada por placas anulares com centro atrófico e bordas hiperqueratóticas, e inclui um grupo heterogêneo de desordens que são na sua maioria herdadas de forma autossômica dominante. O presente caso refere-se a uma paciente feminina de 5 anos de idade, com poroqueratose de Mibelli confirmada histologicamente. A raridade desta desordem, a exuberância clínica e o caráter destrutivo das lesões, o acometimento facial e mucoso pouco usuais nesta forma de poroqueratose e o início na infância precoce motivaram este relato.


Subject(s)
Child, Preschool , Female , Humans , Facial Dermatoses/pathology , Porokeratosis/pathology , Skin/pathology
18.
An. bras. dermatol ; 88(6,supl.1): 39-43, Nov-Dec/2013. tab, graf
Article in English | LILACS | ID: lil-696809

ABSTRACT

The authors describe a case of a female patient with Acral Pseudolymphomatous Angiokeratoma of Children, known as APACHE. It is a rare benign cutaneous disease, of unknown etiology, characterized by multiple, asymptomatic erythematous-violaceous papules and nodules, usually located unilaterally with acral distribution. Today, this denomination is questionable, since there are published reports of this disease in adults and in different locations. Clinically, it is similar to an angiokeratoma, whereas hystologically, it corresponds to a distinct type of pseudolymphoma. The immunohistochemical study is required to distinguish APACHE from cutaneous lymphoma.


Relata-se o caso de uma paciente com diagnóstico de angioqueratoma pseudolinfomatoso acral, conhecido por sua sigla em inglês APACHE - Acral Pseudolymphomatous Angiokeratoma of Children. É uma doença cutânea benigna, rara, de etiologia desconhecida, caracterizada por múltiplas pápulas e nódulos eritêmato-violáceos assintomáticos, de localização geralmente unilateral e acral. Atualmente, questiona-se esta denominação, já que há relatos na literatura do quadro em adultos e em outras localizações. Clinicamente, é similar a um angioqueratoma, porém, histologicamente, corresponde a um tipo distinto de pseudolinfoma. O estudo imuno-histoquímico é necessário para diferenciação dos linfomas cutâneos.


Subject(s)
Child , Female , Humans , Angiokeratoma/pathology , Pseudolymphoma/pathology , Skin Neoplasms/pathology , Biopsy , Immunohistochemistry
19.
An. bras. dermatol ; 88(5): 726-730, out. 2013. tab
Article in English | LILACS | ID: lil-689730

ABSTRACT

BACKGROUND: Basal cell carcinoma is the most common form of cancer in humans. OBJECTIVES: To identify the epidemiology of basal cell carcinoma in Taubaté-SP and verify a possible association between topography and the different histological subtypes of this tumor. METHODS: This was a cross-sectional study conducted at The University Hospital of Taubaté between 01/01/08 and 12/31/09. The study included patients with a confirmed diagnosis of basal cell carcinoma, of both genders, without age restrictions. The variables studied were incidence of basal cell carcinoma, topography, histological subtype, skin color, age and gender. We employed the chi-square test to identify the association between histological subtype and topography, and the student's t test to compare the mean age of onset for the different histological subtypes. RESULTS: The study included 239 individuals. The mean age of the sample was 68.0 years. Male subjects (57.7%) and whites (87.1%) predominated in the study. The predominant histological subtype was nodular (34.7%), followed by the superficial subtype. The most frequent sites of involvement were the head and neck (areas exposed to light), with predominance of the nasal region. The superficial subtype was an exception, as it showed a strong association with unexposed areas like the trunk. The mean age of onset of superficial basal cell carcinoma also differed from that of the other histological subtypes, 63.0 and 69.0 years, respectively. CONCLUSION: The results of this study suggest an association of the superficial histological subtype with younger patients and unexposed areas of the body, linking this type of tumor with a pattern of intermittent sun exposure, more similar to the standard photocarcinogenesis of melanoma. .


FUNDAMENTOS: O carcinoma basocelular é a forma mais comum de câncer em humanos. OBJETIVOS: Identificar a epidemiologia do carcinoma basocelular em Taubaté-SP e verificar possível associação entre a topografia e os diferentes subtipos histológicos deste tumor. MÉTODOS: Estudo transversal e descritivo realizado no Hospital Universitário de Taubaté entre 01/01/08 e 31/12/09. Foram incluídos neste estudo indivíduos com diagnóstico confirmado de carcinoma basocelular, de ambos os gêneros, sem restrição quanto a idade. As variáveis estudadas foram ocorrência do carcinoma basocelular, topografia, subtipo histológico, cor da pele, idade e gênero. Foi utilizado o teste do qui-quadrado para identificar associação entre o subtipo histológico e a topografia, e o teste t de student para comparar a média de idade de acometimento entre os diferentes subtipos histológicos. RESULTADOS: Foram incluídos 239 indivíduos.A média de idade da amostra foi de 68,0 anos. O gênero masculino foi o mais prevalente(57,7%), assim como a pele branca(87,1%).O subtipo histológico predominante foi o nodular(34,7%), seguido do subtipo superficial.A localização mais frequente foi a região de cabeça e pescoço(área fotoexposta), com predomínio da região nasal. Exceção para o subtipo superficial que mostrou forte associação com áreas cobertas como o tronco. A média de idade de incidência do carcinoma basocelular superficial também diferiu dos demais subtipos histológicos, 63.0 e 69.0 anos, respectivamente. CONCLUSÃO: Os resultados sugerem associação do subtipo histológico superficial com faixas etárias mais jovens e áreas cobertas, relacionando o mesmo com um padrão de exposição solar ...


Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Carcinoma, Basal Cell/epidemiology , Skin Neoplasms/epidemiology , Age Distribution , Age Factors , Brazil/epidemiology , Chi-Square Distribution , Cross-Sectional Studies , Carcinoma, Basal Cell/pathology , Sex Distribution , Skin Neoplasms/pathology
20.
Sci. med ; 23(3): 184-186, jul-set. 2013. ilus
Article in Portuguese | LILACS | ID: lil-707308

ABSTRACT

OBJETIVOS: Descrever um caso de onicomicose em criança e alertar para a importância da suspeita clínica e da pesquisa micológica adequada.DESCRIÇÃO DO CASO: Um menino de 1 ano e 8 meses, previamente saudável, apresentava alterações ungueais dos pododáctilos há seis meses. Ao exame dermatológico apresentava hiperqueratose e alteração da coloração das unhas dos pododáctilos, além de lesões eritêmato-descamativas nos espaços interdigitais. Realizou-se exame micológico direto e cultura com material das unhas e da pele, que identificaram um fungo dermatófito, o Microsporum spp. O paciente foi tratado com terbinafina, com resolução completa do quadro.CONCLUSÕES: A onicomicose é a doença mais prevalente nas unhas, porém sua ocorrência na infância é incomum e o fungo do gênero Microsporum como agente causal também é raro.


AIMS: To describe a case of onychomycosis in a child and to alert to the importance of clinical suspicion and an appropriate mycological search.CASE DESCRIPTION: A boy 1 year and 8 months old, previously healthy, had toenail changes for six months. Dermatological examination disclosed hyperkeratosis and discolouration of the nails of the toes, and erythematous, scaly lesions in the interdigital folds. Direct mycological examination and fungal culture were performed and identified a dermatophyte fungus, Microsporum spp. The patient was treated with terbinafine with complete resolution of the condition.CONCLUSIONS: Onychomycosis is the most prevalent disease of the nails, but its occurrence in childhood is uncommon, and the fungus of the genus Microsporum as a causal agent is also rare.


Subject(s)
Child , Child , Microsporum , Onychomycosis , Nails
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